2011
Alkek Awardees for Pilot Projects in Experimental Therapeutics
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Investigator's Name
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Department & Section
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Project Title
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Chen, Johnny, MD
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Surgery
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miR-196a Antagomirs: Novel Therapeutic Agents for Pancreatic Cancer
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Cooper, Thomas, MD
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Pathology/Immunology
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Antisense oligonucleotide therapy for myotonic dystrophy
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Lacorazza, Daniel, PhD
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Pathology/Immunology
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Pre-clinical evaluation of sulforaphane in acute lymphoblastic leukemias
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Li, De-Quan, MD, PhD
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Opthamology
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GDNF as a novel non-corticosteroid anti-inflamatory agent for ocular inflammatory disease
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Lonard, David, PhD
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Molecular and Cell Biology
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Pre-clinical evaluation of bifunctional small hairpin RNAs against steroid receptor coactivator 3/amplified in breast cancer 1 (SRC-3) in tamoxifen and anti-HER2 resistant breast cancers
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Lu, Jian-Ming
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Surgery
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Development of a Xanthine Oxidase Inhibitor from Natural Substances for Gout Therapy
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Matzuk, Martin, MD, PhD
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Pathology/Immunology
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Identification of male contraceptives that target spermatogenesis-specific protein BRDT
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Olmsted-Davis, Elizabeth, PhD
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Hematology/Oncology - CAGT
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Injection of osteoinductive microspheres for rapid repair of long bone injuries
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Song, Yongcheng, PhD
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Pharmacology
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Novel Histone Methyltransferase Inhibitors Targeting Leukemic Stem Cells
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Tweardy, David, MD
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Medicine - Infectious Disease
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Combining Stat3 inhibition and T-cell immunotherapy as a novel treatment for glioblastoma multiforme
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Wehrens, Xander, MD, PhD
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Physiology
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Developing novel ryanodine receptor blockers for the treatment of heart failure and cardiac arrhythmias
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Weigel, Nancy, PhD
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Molecular and Cell Biology
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A new therapeutic approach to eliminate androgen receptor signaling in prostate cancer
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Weisman, Leonard, MD
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Pediatrics - Neonatology
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Development of a ureaplasma DNA vaccine for the prevention and treatment of human infection
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Yao, Cathy, MD
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Surgery
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Mesothelin-Virus Like Particle: Novel Therapeutic Vaccine for Pancreatic Cancer
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Yu-Lee, Li-Yuan, PhD
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Medicine
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Targeting Plk1 with a small molecule inhibitor for castration- resistant prostate cancer
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